We know from the Hebert et al (NEJM 1999, Crit Care Med 2001) that most critically ill patients with anemia should be transfused to maintain a hemoglobin of 7.0-9.0 g/dL and Wu et al (NEJM 2001) showed that elderly people with myocardial infarctions should be transfused to maintain a hematocrit between 30-33%, therefore, should critically ill patients with ESRD be transfused to maintain a hemoglobin between 11-12.0 g/dL, and if not, what should that target be?
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In a patient with symptomatic pulmonary embolism wherein recommended doses of thrombolytic therapy is contraindicated because of recent surgery or GI bleeding, is low-dose, long-term thrombolytic therapy a useful adjunctive measure?
- submitted by Patrick Bui
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